About the Authors

Scott Christley
Department of Computer Science, University of Notre Dame, Notre Dame, Indiana, United States of America

Scott Christley, Mark S Alber
Interdisciplinary Center for the Study of Biocomplexity, University of Notre Dame, Notre Dame, Indiana, United States of America

Mark S Alber
Department of Mathematics, University of Notre Dame, Notre Dame, Indiana, United States of America

Stuart A Newman
Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SAN formulated the biological questions, provided the in vitro data and, with MA, designed the multipixel, multiscale, quasi–3-D representation. MA and SC designed the discrete stochastic model. SC performed the simulations and, with SAN and MA, interpreted the results. SC, MA, and SAN wrote the paper.