About the Authors
Department of Computational Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Department of Bioengineering, Pennsylvania State University, University Park, Pennsylvania, United States of America
University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America
The authors have declared that no competing interests exist.
JL implemented the K-Factor algorithm in Java, generated results, and contributed to writing the manuscript. ZL analyzed the core results and computationally identified specific CRMs. RBS was involved in benchmarking the performance of K-Factor. BJ conceived the project, designed and implemented the underlying methods and datasets, generated results, wrote the manuscript, and supervised the project.