About the Authors

Erwin P Gianchandani

Contributed equally to this work with: Erwin P Gianchandani, Jason A Papin

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

Jason A Papin

Contributed equally to this work with: Erwin P Gianchandani, Jason A Papin

To whom correspondence should be addressed. E-mail: papin@virginia.edu

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

Nathan D Price

Address ¤ Current address: Institute for Systems Biology, Seattle, Washington, United States of America

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Andrew R Joyce

Affiliation Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America

Bernhard O Palsson

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Competing Interests

BOP is on the scientific advisory board of Genomatica, and BOP and the University of California San Diego (UCSD) have a financial interest in Genomatica. Although NIH grant GM68837 has been identified for conflict of interest management based on the overall scope of the project and its potential to benefit to Genomatica, the research findings included in this publication may not necessarily directly relate to the interests of Genomatica.

Author Contributions

EPG, JAP, NDP, ARJ, and BOP conceived and designed the experiments. EPG, JAP, NDP, and ARJ performed the experiments. EPG, JAP, NDP, ARJ, and BOP analyzed the data. EPG, JAP, NDP, ARJ, and BOP wrote the paper.