About the Authors

Julien Racle

Affiliations Laboratory of Computational Systems Biotechnology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland

Flora Picard

Affiliations Université de Toulouse; INSA, UPS, INP; LISBP, Toulouse, France, INRA, UMR792 Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France, CNRS, UMR5504, Toulouse, France

Laurence Girbal

Affiliations Université de Toulouse; INSA, UPS, INP; LISBP, Toulouse, France, INRA, UMR792 Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France, CNRS, UMR5504, Toulouse, France

Muriel Cocaign-Bousquet

cocaign@insa-toulouse.fr (MCB); vassily.hatzimanikatis@epfl.ch (VH)

Affiliations Université de Toulouse; INSA, UPS, INP; LISBP, Toulouse, France, INRA, UMR792 Ingénierie des Systèmes Biologiques et des Procédés, Toulouse, France, CNRS, UMR5504, Toulouse, France

Vassily Hatzimanikatis

cocaign@insa-toulouse.fr (MCB); vassily.hatzimanikatis@epfl.ch (VH)

Affiliations Laboratory of Computational Systems Biotechnology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JR FP LG MCB VH. Performed the experiments: FP LG MCB. Analyzed the data: JR FP LG MCB VH. Wrote the paper: JR FP LG MCB VH. Developed the model: JR VH. Performed the simulations: JR VH.