About the Authors

Kun Hu

khu@bics.bwh.harvard.edu (KH); mzlo@ncu.edu.tw (MTL)

Affiliations Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan

Men-Tzung Lo

khu@bics.bwh.harvard.edu (KH); mzlo@ncu.edu.tw (MTL)

Affiliations Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Research Center for Adaptive Data Analysis, National Central University, Chungli, Taiwan

Chung-Kang Peng

Affiliations Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

Yanhui Liu

Affiliation DynaDx Corporation, Mountain View, California, United States of America

Vera Novak

Affiliations Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KH CKP VN. Performed the experiments: KH VN. Analyzed the data: KH MTL YL. Contributed reagents/materials/analysis tools: KH MTL CKP YL. Wrote the paper: KH MTL VN.