# run_actin_simple.bngl # load and run simple ACTIN model using NF and HPP methods version("2.2.4+") setModelName("actin_simple") readFile({file=>"actin_simple.bngl",allow_actions=>0}) # configure HPP begin parameters # fraction of cell to simulate f 0.01 # population lumping rate, /s k_lump 10000 end parameters begin population maps ADF(a) -> X0001() k_lump Actin(barbed,pointed,p~ATP,d,c~OPEN) -> X0002() k_lump end population maps # actions: saveConcentrations() # simulate with NFsim simulate_nf({ suffix=>"nf", t_end=>1000, n_steps=>200, gml=>10000000, complex=>0 }) # generate partial network and simulate with HPP resetConcentrations() generate_hybrid_model({ suffix=>"hpp", overwrite=>1, verbose=>1, execute=>1,\ actions=>["simulate_nf({ t_end=>1000, n_steps=>200, gml=>10000000, complex=>0 })"] })