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07/18/2018

Research Article

A biophysically detailed computational model of bladder small DRG neuron soma

The small dorsal root ganglion (DRG) neurons of the bladder carry information related to pain from the bladder to the spinal cord. The level of electrical activity of these neurons is generally low but rises in abnormal conditions such as bladder inflammation or spinal cord injury. To investigate the reasons for this hyperactivity, Mandge et al. construct a model of the bladder small DRG neuron soma including its membrane ion channels and intracellular Ca2+ dynamics.

Image credit: Mandge et al.

A biophysically detailed computational model of bladder small DRG neuron soma

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Current Issue June 2018

07/18/2018

Research Article

Stochastic resonance enhances the rate of evidence accumulation during combined brain stimulation and perceptual decision-making

Recent work has revealed that under certain circumstances simple detection performance can be enhanced when an optimal amount of noise is applied to the visual cortex non-invasively using tRNS. Here van der Groen et al. asked whether this stochastic resonance effect also applies to a higher level perceptual decision-making task.

Image credit: van der Groen et al.

Stochastic resonance enhances the rate of evidence accumulation during combined brain stimulation and perceptual decision-making

07/17/2018

Research Article

A quantitative physical model of the TMS-induced discharge artifacts in EEG

Freche et al. show that a simple physical model of skin impedance explains the observed artifact decay, and enables the efficient removal of the artifact signal in an automatable manner. They thus discern the EEG response precisely from about 2 milliseconds after the TMS pulse, showing that the artifact is dominated by capacitive rather than muscular effects.

A quantitative physical model of the TMS-induced discharge artifacts in EEG

Image credit: Freche et al.

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