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April 2014

Phytoplasma-infected flowers of C. roseus produce leaf-like petals that may serve as feeding sites for phytoplasma's vector, the leafhopper. See MacLean et al.

Image Credit: JIC Photography

Essay

Poverty, Disease, and the Ecology of Complex Systems

Calistus N. Ngonghala, Mateusz M. Pluciński, Megan B. Murray, Paul E. Farmer, Christopher B. Barrett, Donald C. Keenan, Matthew H. Bonds

Perspective

The Powers of Participatory Medicine

Barbara Prainsack

Research Articles

Emergent Global Patterns of Ecosystem Structure and Function from a Mechanistic General Ecosystem Model

Michael B. J. Harfoot, Tim Newbold, Derek P. Tittensor, Stephen Emmott, Jon Hutton, Vassily Lyutsarev, Matthew J. Smith, Jörn P. W. Scharlemann, Drew W. Purves

Mismatch Between Birth Date and Vegetation Phenology Slows the Demography of Roe Deer

Floriane Plard, Jean-Michel Gaillard, Tim Coulson, A. J. Mark Hewison, Daniel Delorme, Claude Warnant, Christophe Bonenfant

Related Articles

Phytoplasma Effector SAP54 Hijacks Plant Reproduction by Degrading MADS-box Proteins and Promotes Insect Colonization in a RAD23-Dependent Manner

Allyson M. MacLean, Zigmunds Orlovskis, Krissana Kowitwanich, Anna M. Zdziarska, Gerco C. Angenent, Richard G. H. Immink, Saskia A. Hogenhout

CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease

Guillaume Sarrabayrouse, Céline Bossard, Joe-Marc Chauvin, Anne Jarry, Guillaume Meurette, Elodie Quévrain, Chantal Bridonneau, Laurence Preisser, Karim Asehnoune, Nathalie Labarrière, Frédéric Altare, Harry Sokol, Francine Jotereau

Related Articles

Machine Learning Helps Identify CHRONO as a Circadian Clock Component

Ron C. Anafi, Yool Lee, Trey K. Sato, Anand Venkataraman, Chidambaram Ramanathan, Ibrahim H. Kavakli, Michael E. Hughes, Julie E. Baggs, Jacqueline Growe, Andrew C. Liu, Junhyong Kim, John B. Hogenesch

Related Articles

A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock

Akihiro Goriki, Fumiyuki Hatanaka, Jihwan Myung, Jae Kyoung Kim, Takashi Yoritaka, Shintaro Tanoue, Takaya Abe, Hiroshi Kiyonari, Katsumi Fujimoto, Yukio Kato, Takashi Todo, Akio Matsubara, Daniel Forger, Toru Takumi

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Lowered Insulin Signalling Ameliorates Age-Related Sleep Fragmentation in Drosophila

Athanasios Metaxakis, Luke S. Tain, Sebastian Grönke, Oliver Hendrich, Yvonne Hinze, Ulrike Birras, Linda Partridge

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

Lena Pernas, Yaw Adomako-Ankomah, Anjali J. Shastri, Sarah E. Ewald, Moritz Treeck, Jon P. Boyle, John C. Boothroyd

Related Articles

Discovery of a “White-Gray-Opaque” Tristable Phenotypic Switching System in Candida albicans: Roles of Non-genetic Diversity in Host Adaptation

Li Tao, Han Du, Guobo Guan, Yu Dai, Clarissa J. Nobile, Weihong Liang, Chengjun Cao, Qiuyu Zhang, Jin Zhong, Guanghua Huang

Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis

Natasha Chaudhary, Guillermo A. Gomez, Mark T. Howes, Harriet P. Lo, Kerrie-Ann McMahon, James A. Rae, Nicole L. Schieber, Michelle M. Hill, Katharina Gaus, Alpha S. Yap, Robert G. Parton

The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration

Shiuan Wang, Kai Li Tan, Melina A. Agosto, Bo Xiong, Shinya Yamamoto, Hector Sandoval, Manish Jaiswal, Vafa Bayat, Ke Zhang, Wu-Lin Charng, Gabriela David, Lita Duraine, Kartik Venkatachalam, Theodore G. Wensel, Hugo J. Bellen

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Targeting Of Somatic Hypermutation By immunoglobulin Enhancer And Enhancer-Like Sequences

Jean-Marie Buerstedde, Jukka Alinikula, Hiroshi Arakawa, Jessica J. McDonald, David G. Schatz

Large-Scale Determination of Sequence, Structure, and Function Relationships in Cytosolic Glutathione Transferases across the Biosphere

Susan T. Mashiyama, M. Merced Malabanan, Eyal Akiva, Rahul Bhosle, Megan C. Branch, Brandan Hillerich, Kevin Jagessar, Jungwook Kim, Yury Patskovsky, Ronald D. Seidel, Mark Stead, Rafael Toro, Matthew W. Vetting, Steven C. Almo, Richard N. Armstrong, Patricia C. Babbitt

Related Articles

Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin

Moses Kasembeli, Wilson Chun Yu Lau, Soung-Hun Roh, T. Kris Eckols, Judith Frydman, Wah Chiu, David J. Tweardy