Table of Contents: June 2006

The image was produced by confocal laser scanning microscopy of XY mouse embryonic gonads at 12.5 days post-coitum. Sertoli cells, stained by indirect fluorescence for SOX9 (purple), enclose gonocytes marked by PECAM (green) in testis cords. Testicular vasculature outside cords is visualized by endothelial cell staining for PECAM (See Capel et al.).

Image Credit: Photograph by Yuna Kim


Instituting Change

Hemai Parthasarathy


Restoring Nature's Backbone

Henry Nicholls

Research Articles

X Chromosomes Alternate between Two States prior to Random X-Inactivation

Susanna Mlynarczyk-Evans, Morgan Royce-Tolland, Mary Kate Alexander, Angela A Andersen, Sundeep Kalantry, Joost Gribnau, Barbara Panning

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  1. X Chromosomes' Shape-Shifting Foreshadows Random Inactivation

Chromosomal Distribution of PcG Proteins during Drosophila Development

Nicolas Nègre, Jérôme Hennetin, Ling V Sun, Sergey Lavrov, Michel Bellis, Kevin P White, Giacomo Cavalli

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  1. Polycombing Drosophila for Dynamic Developmental Footprints

High Guanine and Cytosine Content Increases mRNA Levels in Mammalian Cells

Grzegorz Kudla, Leszek Lipinski, Fanny Caffin, Aleksandra Helwak, Maciej Zylicz

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  1. More GC Means More RNA

Dynamic Interaction of TTDA with TFIIH Is Stabilized by Nucleotide Excision Repair in Living Cells

Giuseppina Giglia-Mari, Catherine Miquel, Arjan F Theil, Pierre-Olivier Mari, Deborah Hoogstraten, Jessica M. Y Ng, Christoffel Dinant, Jan H. J Hoeijmakers, Wim Vermeulen

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  1. DNA Repair: Dynamic Defenders against Cancer and Aging
  2. A Tiny Protein Plays a Big Role in DNA Repair

Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination

Yuna Kim, Akio Kobayashi, Ryohei Sekido, Leo DiNapoli, Jennifer Brennan, Marie-Christine Chaboissier, Francis Poulat, Richard R Behringer, Robin Lovell-Badge, Blanche Capel

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  1. Male or Female? It Depends on the Dose

How a Lateralized Brain Supports Symmetrical Bimanual Tasks

Roland S Johansson, Anna Theorin, Göran Westling, Mikael Andersson, Yukari Ohki, Lars Nyberg

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  1. Making Hands Jive: How the Body Manages Hand Coordination

Resistance Evolution to Bt Crops: Predispersal Mating of European Corn Borers

Ambroise Dalecky, Sergine Ponsard, Richard I Bailey, Céline Pélissier, Denis Bourguet

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  1. Mating Patterns and Bt Resistance: The Case of the European Corn Borer

Climate, Deer, Rodents, and Acorns as Determinants of Variation in Lyme-Disease Risk

Richard S Ostfeld, Charles D Canham, Kelly Oggenfuss, Raymond J Winchcombe, Felicia Keesing

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  1. A New View on Lyme Disease: Rodents Hold the Key to Annual Risk

Metabolic Complementarity and Genomics of the Dual Bacterial Symbiosis of Sharpshooters

Dongying Wu, Sean C Daugherty, Susan E Van Aken, Grace H Pai, Kisha L Watkins, Hoda Khouri, Luke J Tallon, Jennifer M Zaborsky, Helen E Dunbar, Phat L Tran, Nancy A Moran, Jonathan A Eisen

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  1. Bacterial Symbionts May Prove a Double-Edged Sword for the Sharpshooter

Book Review%2FScience in the Media

All for All

John Sulston