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Table of Contents: March 2006

A human mammary epithelial cell stained to visualize the microtubule spindles (α-tubulin), centrioles (centrin 2), and chromosomes (DAPI). The image is represented by four different color combinations, modified using Photoshop software. Splitting of centriole pairs in primary cells leads to multipolar spindles and causes mis-segregation of chromosomes during mitosis (aneuploidy). See McDermott et al.

Image Credit: Image by Kimberly M. McDermott

Editorial

Being Positive about Selection

Catriona MacCallum, Emma Hill

Community Page

Plant Virus Biodiversity and Ecology

Jonathan D Wren, Marilyn J Roossinck, Richard S Nelson, Kay Scheets, Michael W Palmer, Ulrich Melcher

Research Articles

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex

Katherine Belov, Janine E Deakin, Anthony T Papenfuss, Michelle L Baker, Sandra D Melman, Hannah V Siddle, Nicolas Gouin, David L Goode, Tobias J Sargeant, Mark D Robinson, Matthew J Wakefield, Shaun Mahony, Joseph G. R Cross, Panayiotis V Benos, Paul B Samollow, Terence P Speed, Jennifer A. Marshall Graves, Robert D Miller

Related Articles

  1. Marsupial Genome Sheds Light on the Evolution of Immunity

p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Kimberly M McDermott, Jianmin Zhang, Charles R Holst, B. Krystyna Kozakiewicz, Veena Singla, Thea D Tlsty

Related Articles

  1. A Key Tumor Suppressor Protein Ensures Proper Chromosome Segregation during Cell Division

Gene Losses during Human Origins

Xiaoxia Wang, Wendy E Grus, Jianzhi Zhang

Related Articles

  1. When Less Is More: Losing Genes on the Path to Becoming Human

Visual Clutter Causes High-Magnitude Errors

Stefano Baldassi, Nicola Megna, David C Burr

Related Articles

  1. When Seeing Is Misleading: Clutter Leads to High-Confidence Errors

Removing the Threat of Diclofenac to Critically Endangered Asian Vultures

Gerry Swan, Vinasan Naidoo, Richard Cuthbert, Rhys E Green, Deborah J Pain, Devendra Swarup, Vibhu Prakash, Mark Taggart, Lizette Bekker, Devojit Das, Jörg Diekmann, Maria Diekmann, Elmarié Killian, Andy Meharg, Ramesh Chandra Patra, Mohini Saini, Kerri Wolter

Related Articles

  1. Switching Drugs for Livestock May Help Save Critically Endangered Asian Vultures

Complete Mitochondrial Genome and Phylogeny of Pleistocene MammothMammuthus primigenius

Evgeny I Rogaev, Yuri K Moliaka, Boris A Malyarchuk, Fyodor A Kondrashov, Miroslava V Derenko, Ilya Chumakov, Anastasia P Grigorenko

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  1. The Year of the Mammoth
  2. Reading the Evolutionary History of the Woolly Mammoth in Its Mitochondrial Genome

A Stress Surveillance System Based on Calcium and Nitric Oxide in Marine Diatoms

Assaf Vardi, Fabio Formiggini, Raffaella Casotti, Alessandra De Martino, François Ribalet, Antonio Miralto, Chris Bowler

Related Articles

  1. Diatoms Rely on Sophisticated Signaling Systems for Population Control

Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor Dysfunction

Dominique Helmlinger, Sara Hardy, Gretta Abou-Sleymane, Adrien Eberlin, Aaron B Bowman, Anne Gansmüller, Serge Picaud, Huda Y Zoghbi, Yvon Trottier, Làszlò Tora, Didier Devys

Related Articles

  1. Polyglutamine Leads to Altered Chromatin Architecture and Neurodegeneration

The Cutaneous Rabbit Illusion Affects Human Primary Sensory Cortex Somatotopically

Felix Blankenburg, Christian C Ruff, Ralf Deichmann, Geraint Rees, Jon Driver

Related Articles

  1. Classic Illusion Sheds New Light on the Neural Site of Tactile Perception

Correspondence and Other Communications

Neuromedin U and Its Putative Drosophila Homolog hugin

Christoph Melcher, Rüdiger Bader, Steffen Walther, Oleg Simakov, Michael J Pankratz

Book Review%2FScience in the Media

Toward a Climate of Scientific Integrity

Beth A Fischer, Michael J Zigmond