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Table of Contents: September 2005

The fruit fly Drosophila melanogaster, like other multicellular organisms, decides whether to feed or not based on external stimuli, including gustatory information. Displayed is a composite fluorescence image of a Drosophila brain showing a population of neurons interconnecting taste input with higher brain centers, thereby modulating the fly's feeding behavior. See Melcher and Pankratz.

Image Credit: Image by Christoph Melcher

Editorials

Replication Publication

Mark Patterson, Lon Cardon

Essays

Science Star over Asia

Chris Y. H Tan

Book Reviews/Science in the Media

A Night Out with the Nerds

Sandra Knapp, James Mallet

Community Pages

Peer Review—The Newcomers' Perspective

Gaell Mainguy, Mohammad R Motamedi, Daniel Mietchen

Research Articles

Functional Identification of Catalytic Metal Ion Binding Sites within RNA

James L Hougland, Alexander V Kravchuk, Daniel Herschlag, Joseph A Piccirilli

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The Genomics of Disulfide Bonding and Protein Stabilization in Thermophiles

Morgan Beeby, Brian D O'Connor, Carsten Ryttersgaard, Daniel R Boutz, L. Jeanne Perry, Todd O Yeates

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  1. Genomics Helps Explain Why Some Like It Hot

Speciation and Gene Flow between Snails of Opposite Chirality

Angus Davison, Satoshi Chiba, Nicholas H Barton, Bryan Clarke

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  1. Speciation Begins, but Doesn't End, with the Twist of a Shell

Genomic Islands of Speciation in Anopheles gambiae

Thomas L Turner, Matthew W Hahn, Sergey V Nuzhdin

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  1. Islands in the Genome Promote Speciation

Whole-Genome Analysis of Human Influenza A Virus Reveals Multiple Persistent Lineages and Reassortment among Recent H3N2 Viruses

Edward C Holmes, Elodie Ghedin, Naomi Miller, Jill Taylor, Yiming Bao, Kirsten St George, Bryan T Grenfell, Steven L Salzberg, Claire M Fraser, David J Lipman, Jeffery K Taubenberger

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  1. Enlisting Genomics to Understand Flu Evolution

Malaria Infection Increases Attractiveness of Humans to Mosquitoes

Renaud Lacroix, Wolfgang R Mukabana, Louis Clement Gouagna, Jacob C Koella

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  1. To Mosquitoes, People with Malaria Smell Like Dinner

Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell

Luciano Conti, Steven M Pollard, Thorsten Gorba, Erika Reitano, Mauro Toselli, Gerardo Biella, Yirui Sun, Sveva Sanzone, Qi-Long Ying, Elena Cattaneo, Austin Smith

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  1. A Recipe for Self-Renewing Brain

The Temporal Requirements for Insulin Signaling During Development in Drosophila

Alexander W Shingleton, Jayatri Das, Lucio Vinicius, David L Stern

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  1. For Insulin Signaling Pathways in Flies, Size Matters

Aging and Gene Expression in the Primate Brain

Hunter B Fraser, Philipp Khaitovich, Joshua B Plotkin, Svante Pääbo, Michael B Eisen

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  1. Gene Expression in the Aging Brain

Lack of Support for the Association between GAD2 Polymorphisms and Severe Human Obesity

Michael M Swarbrick, Björn Waldenmaier, Len A Pennacchio, Denise L Lind, Martha M Cavazos, Frank Geller, Raphael Merriman, Anna Ustaszewska, Mary Malloy, André Scherag, Wen-Chi Hsueh, Winfried Rief, Franck Mauvais-Jarvis, Clive R Pullinger, John P Kane, Robert Dent, Ruth McPherson, Pui-Yan Kwok, Anke Hinney, Johannes Hebebrand, Christian Vaisse

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  1. A Genetic Link to Obesity: The Numbers Don't Add Up for GAD2