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Table of Contents: August 2005

Bacterial DNA was collected from a pumping site only a few meters from the location of this underwater shot in the Red Sea. Fragments of this DNA were used to construct one of the bacterial artificial chromosome libraries described in Sabehi et al.

Image Credit: Photograph by Boaz Harel

Editorials

Measures of Impact

Hemai Parthasarathy

Features

Prices for Ingenuity

Bill O'Neill

Community Pages

Bioinformatics and Data Management Support for Environmental Genomics

Dawn Field, Bela Tiwari, Jason Snape

Research Articles

Evolution, Systematics, and Phylogeography of Pleistocene Horses in the New World: A Molecular Perspective

Jaco Weinstock, Eske Willerslev, Andrei Sher, Wenfei Tong, Simon Y.W Ho, Dan Rubenstein, John Storer, James Burns, Larry Martin, Claudio Bravi, Alfredo Prieto, Duane Froese, Eric Scott, Lai Xulong, Alan Cooper

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The Genome Sequence of Rickettsia felis Identifies the First Putative Conjugative Plasmid in an Obligate Intracellular Parasite

Hiroyuki Ogata, Patricia Renesto, Stéphane Audic, Catherine Robert, Guillaume Blanc, Pierre-Edouard Fournier, Hugues Parinello, Jean-Michel Claverie, Didier Raoult

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  1. Using the Genomic Shortcut to Predict Bacterial Behavior

Prevalence-Dependent Costs of Parasite Virulence

Stephanie Bedhomme, Philip Agnew, Yuri Vital, Christine Sidobre, Yannis Michalakis

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  1. Prevalence of Infection in a Population Can Shape Parasite Virulence

New Insights into Metabolic Properties of Marine Bacteria Encoding Proteorhodopsins

Gazalah Sabehi, Alexander Loy, Kwang-Hwan Jung, Ranga Partha, John L Spudich, Tal Isaacson, Joseph Hirschberg, Michael Wagner, Oded Béjà

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  1. Light-Sensing Protein Illuminates Sun-Loving Ocean Bacteria

A Conserved Mechanism for Sulfonucleotide Reduction

Kate S Carroll, Hong Gao, Huiyi Chen, C. David Stout, Julie A Leary, Carolyn R Bertozzi

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  1. Reducing the Mysteries of Sulfur Metabolism

Functional Analysis of Human Hematopoietic Stem Cell Gene Expression Using Zebrafish

Craig E Eckfeldt, Eric M Mendenhall, Catherine M Flynn, Tzu-Fei Wang, Michael A Pickart, Suzanne M Grindle, Stephen C Ekker, Catherine M Verfaillie

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  1. Fish and Chips: A Fast Track to Understanding Blood Development

The Ews-ERG Fusion Protein Can Initiate Neoplasia from Lineage-Committed Haematopoietic Cells

Rosalind Codrington, Richard Pannell, Alan Forster, Lesley F Drynan, Angelika Daser, Nati Lobato, Markus Metzler, Terence H Rabbitts

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  1. Cancer-Causing Genes Can Convert Even the Most Committed Cells

De Novo Formation of Left–Right Asymmetry by Posterior Tilt of Nodal Cilia

Shigenori Nonaka, Satoko Yoshiba, Daisuke Watanabe, Shingo Ikeuchi, Tomonobu Goto, Wallace F Marshall, Hiroshi Hamada

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  2. How Do Embryos Know Left from Right?

Diverse Modes of Axon Elaboration in the Developing Neocortex

Carlos Portera-Cailliau, Robby M Weimer, Vincenzo De Paola, Pico Caroni, Karel Svoboda

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  1. Creating a Window into the Developing Brain: Observing Axon Growth in Live Mice

Dopamine-Independent Locomotor Actions of Amphetamines in a Novel Acute Mouse Model of Parkinson Disease

Tatyana D Sotnikova, Jean-Martin Beaulieu, Larry S Barak, William C Wetsel, Marc G Caron, Raul R Gainetdinov

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  1. A Mouse Model for Parkinson Disease