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Table of Contents: June 2005

Malaria is transmitted to people and animals by mosquitoes. Malarial sporozoites develop inside oocysts and are released in large numbers into the hemocoel of Anopheles stephensi mosquitoes. This false-colored electron micrograph shows a sporozoite migrating through the cytoplasm of midgut epithelia. See Frevert et al.

Image Credit: Image by Ute Frevert; false color by Margaret Shear

Essays

The Evolution of Norms

Paul R Ehrlich, Simon A Levin

Features

Book Reviews/Science in the Media

Community Pages

Guidelines for Negotiating Scientific Collaboration

Neil R Smalheiser, Guy A Perkins, Steve Jones

Research Articles

A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees

Rasmus Nielsen, Carlos Bustamante, Andrew G Clark, Stephen Glanowski, Timothy B Sackton, Melissa J Hubisz, Adi Fledel-Alon, David M Tanenbaum, Daniel Civello, Thomas J White, John J. Sninsky, Mark D Adams, Michele Cargill

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A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control

Štěpánka Vaňáčová, Jeannette Wolf, Georges Martin, Diana Blank, Sabine Dettwiler, Arno Friedlein, Hanno Langen, Gérard Keith, Walter Keller

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  1. An Enzyme That Oversees RNA Quality Control

A Three-Stemmed mRNA Pseudoknot in the SARS Coronavirus Frameshift Signal

Ewan P Plant, Gabriela C Pérez-Alvarado, Jonathan L Jacobs, Bani Mukhopadhyay, Mirko Hennig, Jonathan D Dinman

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  1. New Frameshifting Pseudoknot Found in SARS Virus
  2. Pseudoknots: RNA Structures with Diverse Functions

Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance

Ryan T Cirz, Jodie K Chin, David R Andes, Valérie de Crécy-Lagard, William A Craig, Floyd E Romesberg

Related Articles

  1. Bacterial SOS May Be the Key to Combating Antibiotic Resistance

Intravital Observation of Plasmodium berghei Sporozoite Infection of the Liver

Ute Frevert, Sabine Engelmann, Sergine Zougbédé, Jörg Stange, Bruce Ng, Kai Matuschewski, Leonard Liebes, Herman Yee

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  1. Tracking a Killer: In Vivo Microscopy Reveals Details on the Life Cycle of Malarial Parasites

Engineering a Dimeric Caspase-9: A Re-evaluation of the Induced Proximity Model for Caspase Activation

Yang Chao, Eric N Shiozaki, Srinivasa M Srinivasula, Daniel J Rigotti, Robert Fairman, Yigong Shi

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  1. Proximity- or Conformation-Induced Caspase Activation?

Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury

Manfred Thiel, Alexander Chouker, Akio Ohta, Edward Jackson, Charles Caldwell, Patrick Smith, Dmitry Lukashev, Iris Bittmann, Michail V Sitkovsky

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  1. Hypoxia to the Rescue: When Oxygen Therapies Backfire
  2. Hooray for Hypoxia?

Determination of Stromal Signatures in Breast Carcinoma

Robert B West, Dimitry S. A Nuyten, Subbaya Subramanian, Torsten O Nielsen, Christopher L Corless, Brian P Rubin, Kelli Montgomery, Shirley Zhu, Rajiv Patel, Tina Hernandez-Boussard, John R Goldblum, Patrick O Brown, Marc van de Vijver, Matt van de Rijn

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  1. Microarrays Highlight Tumor–Connective Tissue Interactions in Cancer Outcomes

Neuronal Migration and Ventral Subtype Identity in the Telencephalon Depend on SOX1

Antigoni Ekonomou, Ilias Kazanis, Stavros Malas, Heather Wood, Pavlos Alifragis, Myrto Denaxa, Domna Karagogeos, Andrew Constanti, Robin Lovell-Badge, Vasso Episkopou

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  1. Migration and Fate Specification in the Ventral Striatum

Function of a Fly Motion-Sensitive Neuron Matches Eye Movements during Free Flight

Roland Kern, J. H van Hateren, Christian Michaelis, Jens Peter Lindemann, Martin Egelhaaf

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  1. Fly Movie Theater Reveals Secrets of How Insects See the World