Table of Contents: August 2004

Sites of retroviral integration are shown arrayed on the human chromosomes. Orange "lollipops" indicate sites of HIV integration; green, MLV; and pink, ASLV. The density of genes on each chromosome is shown by the blue shading. The background shows a high-density microarray such as those used to study the relationship between integration and gene activity. (See Mitchell, et al.)

Image Credit: Chromosome image by Huaming Chen, Salk Institute. Design by Jamie Simon, Salk Institute


Extinction, Slime, and Bottoms

Sean Nee


Opening a Window to the Autistic Brain

Kendall Powell

Journal Club

Research Articles

Nicotine's Defensive Function in Nature

Anke Steppuhn, Klaus Gase, Bernd Krock, Rayko Halitschke, Ian T Baldwin

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Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences

Rick S Mitchell, Brett F Beitzel, Astrid R. W Schroder, Paul Shinn, Huaming Chen, Charles C Berry, Joseph R Ecker, Frederic D Bushman

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Konstantinos Zarbalis, Scott R May, Yiguo Shen, Marc Ekker, John L. R Rubenstein, Andrew S Peterson

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The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1γ, an Essential Regulator of Hematopoiesis

David G Ransom, Nathan Bahary, Knut Niss, David Traver, Caroline Burns, Nikolaus S Trede, Noelle Paffett-Lugassy, Walter J Saganic, C. Anthoney Lim, Candace Hersey, Yi Zhou, Bruce A Barut, Shuo Lin, Paul D Kingsley, James Palis, Stuart H Orkin, Leonard I Zon

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