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Open Access
Peer-reviewed
Research Article
A Simple Genetic Architecture Underlies Morphological Variation in Dogs
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Adam R. Boyko ,
Contributed equally to this work with: Adam R. Boyko, Pascale Quignon, Lin Li
Affiliations Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Pascale Quignon ,
Contributed equally to this work with: Adam R. Boyko, Pascale Quignon, Lin Li
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Lin Li ,
Contributed equally to this work with: Adam R. Boyko, Pascale Quignon, Lin Li
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Jeffrey J. Schoenebeck,
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Jeremiah D. Degenhardt,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Kirk E. Lohmueller,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Keyan Zhao,
Affiliations Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Abra Brisbin,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Heidi G. Parker,
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Bridgett M. vonHoldt,
Affiliation Department of Ecology and Environmental Biology, University of California, Los Angeles, California, United States of America
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Michele Cargill,
Affiliation Affymetrix Corporation, Santa Clara, California, United States of America
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Adam Auton,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Andy Reynolds,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Abdel G. Elkahloun,
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Marta Castelhano,
Affiliation Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
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Dana S. Mosher,
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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Nathan B. Sutter,
Affiliations Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America
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Gary S. Johnson,
Affiliation Department of Veterinary Pathobiology, University of Missouri, Columbia, Missouri, United States of America
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John Novembre,
Affiliation Department of Ecology and Environmental Biology, University of California, Los Angeles, California, United States of America
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Melissa J. Hubisz,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Adam Siepel,
Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Robert K. Wayne,
Affiliation Department of Ecology and Environmental Biology, University of California, Los Angeles, California, United States of America
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Carlos D. Bustamante ,
* E-mail: cdbustam@stanford.edu (CDB); eostrand@mail.nih.gov (EAO)
¶These authors co-directed the work.
Affiliations Department of Genetics, Stanford School of Medicine, Stanford, California, United States of America, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America
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Elaine A. Ostrander
* E-mail: cdbustam@stanford.edu (CDB); eostrand@mail.nih.gov (EAO)
¶These authors co-directed the work.
Affiliation Cancer Genetic Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
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A Simple Genetic Architecture Underlies Morphological Variation in Dogs
- Adam R. Boyko,
- Pascale Quignon,
- Lin Li,
- Jeffrey J. Schoenebeck,
- Jeremiah D. Degenhardt,
- Kirk E. Lohmueller,
- Keyan Zhao,
- Abra Brisbin,
- Heidi G. Parker,
- Bridgett M. vonHoldt
- Published: August 10, 2010
- https://doi.org/10.1371/journal.pbio.1000451