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Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

  • Shadmehr Demehri ,

    To whom correspondence should be addressed. E-mail: Kopan@wustl.edu (RK); demehris@msnotes.wustl.edu (SD)

    Affiliations Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America , Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Zhenyi Liu,

    Affiliation Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Jonghyeob Lee,

    ¤ Current address: Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America

    Affiliation Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Meei-Hua Lin,

    Affiliation Renal Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Seth D Crosby,

    Affiliation Genome Sequencing Center, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Christopher J Roberts,

    Affiliation Rosetta Inpharmatics, Seattle, Washington, United States of America

  • Perry W Grigsby,

    Affiliation Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Jeffrey H Miner,

    Affiliation Renal Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America

  • Andrew G Farr,

    Affiliation Department of Biological Structure and Department of Immunology, University of Washington, Seattle, Washington, United States of America

  • Raphael Kopan

    To whom correspondence should be addressed. E-mail: Kopan@wustl.edu (RK); demehris@msnotes.wustl.edu (SD)

    Affiliations Department of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri, United States of America , Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri, United States of America

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

  • Shadmehr Demehri, 
  • Zhenyi Liu, 
  • Jonghyeob Lee, 
  • Meei-Hua Lin, 
  • Seth D Crosby, 
  • Christopher J Roberts, 
  • Perry W Grigsby, 
  • Jeffrey H Miner, 
  • Andrew G Farr, 
  • Raphael Kopan
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