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Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

  • Takaharu Okada ,

    Contributed equally to this work with: Takaharu Okada, Mark J Miller

    Affiliation Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

  • Mark J Miller ,

    Contributed equally to this work with: Takaharu Okada, Mark J Miller

    Current address: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America

    Affiliation Department of Physiology and Biophysics, University of California, Irvine, California, United States of America

  • Ian Parker,

    Affiliation Department of Neurobiology and Behavior, University of California, Irvine, California, United States of America

  • Matthew F Krummel,

    Affiliation Department of Pathology, University of California, San Francisco, California, United States of America

  • Margaret Neighbors,

    Current address: Maxygen, Redwood City, California, United States of America

    Affiliation Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

  • Suzanne B Hartley,

    Current address: Ainslie, ACT, Australia

    Affiliation Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

  • Anne O'Garra,

    Current address: Laboratory of Immunoregulation, The National Institute for Medical Research, London, United Kingdom

    Affiliation Department of Immunobiology, DNAX Research Institute, Palo Alto, California, United States of America

  • Michael D Cahalan ,

    To whom correspondence should be addressed. E-mail: mcahalan@uci.edu (MC), Email: cyster@itsa.ucsf.edu (JC)

    Affiliation Department of Physiology and Biophysics, University of California, Irvine, California, United States of America

  • Jason G Cyster

    To whom correspondence should be addressed. E-mail: mcahalan@uci.edu (MC), Email: cyster@itsa.ucsf.edu (JC)

    Affiliation Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California, United States of America

Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

  • Takaharu Okada, 
  • Mark J Miller, 
  • Ian Parker, 
  • Matthew F Krummel, 
  • Margaret Neighbors, 
  • Suzanne B Hartley, 
  • Anne O'Garra, 
  • Michael D Cahalan, 
  • Jason G Cyster
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