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Key scientific issues in developing drinking water guidelines for perfluoroalkyl acids: Contaminants of emerging concern

Fig 2

Predicted increases in serum PFOA concentrations from consumption of drinking water with various concentrations of PFOA.

Predicted serum PFOA concentrations from consumption at mean [30] and upper percentile drinking water ingestion rates, as compared to median and 95th serum PFOA concentration percentiles from NHANES [23]. Predictions are based on the clearance factor for PFOA (0.14 ml/kg/day), which relates PFOA dose (ng/kg/day) to serum PFOA concentration (ng/ml) [3133]. PFOA, perfluorooctanoic acid; NHANES, National Health and Nutrition Examination Survey.

Fig 2

doi: https://doi.org/10.1371/journal.pbio.2002855.g002