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Lef1-dependent hypothalamic neurogenesis inhibits anxiety

Fig 3

Lef1 regulates growth and anxiety in zebrafish.

(A) Size of 30 days post-fertilization (dpf) fish when raised at 5 fish per tank separated by genotype. n = 25, 30 for control and mutant, respectively. (B-F) Novel tank diving test. Sixteen dpf larvae were analyzed between 1–3 minutes (C-E) or 4–6 minutes (F) after entering a novel tank. n = 9 for both controls and mutants. Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ns. P > 0.05 by unpaired Student t tests. Raw data can be found in S1 Data.

Fig 3