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Circadian and Social Cues Regulate Ion Channel Trafficking

Figure 8

Rundown of sodium current and washout of CQ effect.

(A) Decrease in peak Na+ current following 30 min exposure to Saline, CQ, NEM, and BFA. (B) Washing out CQ while maintaining ACTH in the bath saline led to increased INa magnitude (n = 4). (C) Washing out CQ with normal saline for 60 min did not produce recovery of INa, but subsequent addition of ACTH increased INa magnitude (n = 4).

Figure 8