High Functional Diversity in Mycobacterium tuberculosis Driven by Genetic Drift and Human Demography
The branches are colored according to the main lineages defined previously based on our genomic deletion analysis, except for the animal-adapted strains, which are indicated in orange. The main clades are labeled according to their dominance in particular geographic areas. The branch leading to M. canettii has been truncated in the figure because of the large numbers of changes that separate this hypothesized outgroup from the rest of the phylogeny (Table S4). Ancient and modern strain lineages are indicated. The green and brown lineages correspond to strains traditionally known as M. africanum .