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Metagenome Annotation Using a Distributed Grid of Undergraduate Students

Figure 4

Comparison of Student (Annotathon) Versus Literature (GOS) Annotations

(A) Taxonomic domain-level classifications, determined either by students using phylogenetic tree reconstructions (Annotathon, 182 sequences classified) or by an automatic BLAST-based scheme (GOS, 5,058,757 sequences classified [4]). (B) Distribution of sequences across bacteria taxa. Proportions are determined either by students using phylogenetic tree reconstructions (Annotathon, 182 sequences classified) or by 16S-based estimates (GOS, 4,125 sequences classified [3]). (C) Gene products functional classifications. Proportions are determined either by students (Annotathon, 685 sequences classified) or by automatic TIGR (The Institute for Genomic Research) role assignment (GOS, 760,659 sequences classified [2]). Only categories from each partition that could be matched are shown.

Figure 4

doi: https://doi.org/10.1371/journal.pbio.0060296.g004