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Mapping the Structural Core of Human Cerebral Cortex

Figure 6

Modularity and Hub Classification

The modularity was derived from the average regional connection matrix. Modules are listed in Table S1.

(A) The plot shows a dorsal view, with nodes representing anatomical subregions. The spatial position of each region corresponds to the center of mass coordinates calculated from participant A, scan 2 (as seen in Figure 4C). Six modules are shown as gray circles centered on their center of mass and sized according to their number of members. Edges correspond to the average connection densities of each region with the member regions of each of the six modules, plotted between that region's spatial coordinates and the center of mass of each module Connector hubs are defined as regions with above average strength and a participation index p ≥ 0.3, indicating a high proportion of cross-module connectivity. These regions are marked as filled yellow circles. Provincial hubs have above-average strength and P < 0.3; they are marked as unfilled yellow circles.

(B) Connector hubs obtained from analyses of high-resolution connection matrices. ROIs are displayed according to how consistently a given ROI was identified as a connector hub across participants.

Figure 6

doi: https://doi.org/10.1371/journal.pbio.0060159.g006