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Mapping the Structural Core of Human Cerebral Cortex

Figure 3

High-Resolution Connection Matrix, Network Layout and Connectivity Backbone (Participant A, scan 2)

(A) Matrix of fiber densities (connection weights) between all pairs of n = 998 ROIs. ROIs are plotted by cerebral hemispheres, with right-hemispheric ROIs in the upper left quadrant, left-hemispheric ROIs in the lower right quadrant, and interhemispheric connections in the upper right and lower left quadrants. The color bars at the left and bottom of the matrix correspond to the colors of the 66 anatomical subregions shown in Figure 1. All connections are symmetric and displayed with a logarithmic color map.

(B) Kamada-Kawai force-spring layout of the connectivity backbone. Labels indicating anatomical subregions are placed at their respective centers of mass. Nodes (individual ROIs) are coded according to strength and edges are coded according to connection weight (see legend).

(C) Dorsal and lateral views of the connectivity backbone. Node and edge coding as in (B).

Figure 3

doi: https://doi.org/10.1371/journal.pbio.0060159.g003