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Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes

Figure 4

MDS Plots of Experimental and Simulated Heterologous Distances

(A) The MDS plot provides a 2D distance map of the mean locations of the IGCs of all heterologous CTs established from 54 G0 nuclei (for further explanations see Materials and Methods). The units (dimension 1 and dimension 2) are arbitrary.

(B) MDS plot for all heterologous PCs in 28 prometaphase rosettes.

(C) MDS plot for statistically placed CTs in 50 SCD model nuclei.

(D) MDS plot for 50 model nuclei with points randomly placed with a random number generator.

Figure 4

doi: https://doi.org/10.1371/journal.pbio.0030157.g004