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Developmental Context Determines Latency of MYC-Induced Tumorigenesis

Figure 2

MYC-Induced Hepatic Tumors Are Invasive and Metastatic

(A) Adult mouse with MYC-induced liver tumor that has metastasized to the abdomen and the lungs.

(B) Histology of an adult MYC-induced lung metastasis.

(C) Histology of an adult MYC-induced liver tumor.

(D) Gross pathology of a liver tumor from a neonatal host transplanted subcutaneously into a scid mouse.

Figure 2

doi: https://doi.org/10.1371/journal.pbio.0020332.g002