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Open Access
Peer-reviewed
Research Article
A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning
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Jack Jing Lin Wong,
Affiliations Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore, Graduate School for Integrated Sciences and Engineering, Centre for Life Sciences, National University of Singapore (NUS), Singapore
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Song Li ,
Contributed equally to this work with: Song Li, Edwin Kok Hao Lim, Yan Wang
Affiliations Graduate School for Integrated Sciences and Engineering, Centre for Life Sciences, National University of Singapore (NUS), Singapore, Neuroscience and Behavioral Disorder Program, Duke–NUS Graduate Medical School Singapore, Singapore
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Edwin Kok Hao Lim ,
Contributed equally to this work with: Song Li, Edwin Kok Hao Lim, Yan Wang
Affiliation Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore
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Yan Wang ,
Contributed equally to this work with: Song Li, Edwin Kok Hao Lim, Yan Wang
Affiliation Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore
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Cheng Wang,
Affiliation Neuroscience and Behavioral Disorder Program, Duke–NUS Graduate Medical School Singapore, Singapore
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Heng Zhang,
Affiliation Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore
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Daniel Kirilly,
Affiliation Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore
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Chunlai Wu,
Affiliation Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America
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Yih-Cherng Liou,
Affiliations Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore, Graduate School for Integrated Sciences and Engineering, Centre for Life Sciences, National University of Singapore (NUS), Singapore
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Hongyan Wang,
Affiliations Graduate School for Integrated Sciences and Engineering, Centre for Life Sciences, National University of Singapore (NUS), Singapore, Neuroscience and Behavioral Disorder Program, Duke–NUS Graduate Medical School Singapore, Singapore, Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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Fengwei Yu
* E-mail: fengwei@tll.org.sg
Affiliations Temasek Life Sciences Laboratory and Department of Biological Sciences, National University of Singapore, Singapore, Graduate School for Integrated Sciences and Engineering, Centre for Life Sciences, National University of Singapore (NUS), Singapore, Neuroscience and Behavioral Disorder Program, Duke–NUS Graduate Medical School Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
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A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning
- Jack Jing Lin Wong,
- Song Li,
- Edwin Kok Hao Lim,
- Yan Wang,
- Cheng Wang,
- Heng Zhang,
- Daniel Kirilly,
- Chunlai Wu,
- Yih-Cherng Liou,
- Hongyan Wang
- Published: September 17, 2013
- https://doi.org/10.1371/journal.pbio.1001657