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Confounding variables

Posted by SABRE on 06 Aug 2013 at 09:03 GMT

Is there any particular reason why 'temperature' was chosen from the numerous environmental factors for control as the one confounding variable to be included in the inclusion criteria?

No competing interests declared.

RE: Confounding variables

mmacleod1975 replied to SABRE on 10 Sep 2013 at 00:07 GMT

In stroke modelling, the temperature of the animal, if not regulated, will fall during the procedure. This can have protective effects which inflate the apparent effect of the drug being tested. Therefore, high quality studies will report that they took measures (usually warming the animal with a heating blanket and monitoring the temperature) to ensure it remains constant throughout the experiment.

Competing interests declared: I'm one of the authors of the original article