The Germinal Center Kinase TNIK Is Required for Canonical NF-κB and JNK Signaling in B-Cells by the EBV Oncoprotein LMP1 and the CD40 Receptor

Open Access

Peer-reviewed

Research Article

Anna Shkoda ,

Contributed equally to this work with: Anna Shkoda, Jennifer A. Town

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
⨯
Jennifer A. Town ,

Contributed equally to this work with: Anna Shkoda, Jennifer A. Town

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
⨯
Janine Griese,

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
⨯
Michael Romio,

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
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Hakan Sarioglu,

Affiliation Research Unit Protein Science, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
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Thomas Knöfel,

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
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Fabian Giehler,

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
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Arnd Kieser

* E-mail: a.kieser@helmholtz-muenchen.de

Affiliation Research Unit Gene Vectors, Helmholtz Zentrum München - German Research Center for Environmental Health, München, Germany
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Reader Comments

,
http://plosbiology.org/article/info:doi/10.1371/journal.pbio.1001376#article1.body1.sec1.p4

Some reference numbers were omitted from the text. The correct references are: [25,26,28-33].

No competing interests declared.

Immunoprecipitation
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Transcription factors
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B cells
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Transfection
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Small interfering RNA
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c-Jun N-terminal kinase signaling cascade
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Immunoblotting
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Phosphorylation
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