TY - JOUR T1 - DNA-Dependent Protein Kinase Inhibits AID-Induced Antibody Gene Conversion A1 - Cook, Adam J. L A1 - Raftery, Joanna M A1 - Lau, K. K. Edwin A1 - Jessup, Andrew A1 - Harris, Reuben S A1 - Takeda, Shunichi A1 - Jolly, Christopher J Y1 - 2007/03/13 N2 - Affinity maturation and class switching of antibodies requires AID-dependent hypermutation of Ig V(D)J rearrangements. This process is shown here to involve double-strand DNA breaks that recruit repair machinery. JF - PLOS Biology JA - PLOS Biology VL - 5 IS - 4 UR - https://doi.org/10.1371/journal.pbio.0050080 SP - e80 EP - PB - Public Library of Science M3 - doi:10.1371/journal.pbio.0050080 ER -