About the Authors
- Michal Mielcarek
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Christian Landles
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Andreas Weiss
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Affiliation Novartis Institutes for BioMedical Research, Neuroscience Discovery, Basel, Switzerland
- Amyaouch Bradaia
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Affiliation Neuroservice, Aix en Provence, France
- Tamara Seredenina
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Affiliation Brain Mind Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
- Linda Inuabasi
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Georgina F. Osborne
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Kristian Wadel
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Affiliation Neuroservice, Aix en Provence, France
- Chrystelle Touller
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Affiliation Neuroservice, Aix en Provence, France
- Rachel Butler
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Current address: Nuffield Laboratory of Ophthalmology, University of Oxford, The John Radcliffe Hospital, Oxford, United Kingdom.
Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Janette Robertson
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Sophie A. Franklin
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Donna L. Smith
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Larry Park
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Affiliation CHDI Management Inc./CHDI Foundation, Los Angeles, California, United States of America
- Paul A. Marks
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Affiliation Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
- Erich E. Wanker
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Affiliation Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Berlin, Germany
- Eric N. Olson
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Affiliation Department of Molecular Biology, Southwestern University, Dallas, Texas, United States of America
- Ruth Luthi-Carter
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Affiliation Brain Mind Institute, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland
- Herman van der Putten
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Affiliation Novartis Institutes for BioMedical Research, Neuroscience Discovery, Basel, Switzerland
- Vahri Beaumont
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Affiliation CHDI Management Inc./CHDI Foundation, Los Angeles, California, United States of America
- Gillian P. Bates
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* E-mail: gillian.bates@kcl.ac.uk
Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
Competing Interests
Andreas Weiss and Herman van der Putten are employees of Novartis AG and potentially own shares in the company. Neuroservice conducted the research through a fee-for-service agreement for the CHDI Foundation. Larry Park and Vahri Beaumont are employed by CHDI Management Inc. to provide consulting services to CHDI Foundation. Amyaouch Bradaia, Kristian Wadel, and Chrystelle Touller are employees of Neuroservice. There are no patents, products in development, or marketed products to declare. We fully adhere to all the PLoS Biology policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MM HvdP VB GPB. Performed the experiments: MM CL AW AB TS LI GFO KW CT RB JR SAF DLS RLC. Analyzed the data: MM CL AW AB TS LP RLC HvdP VB GPB. Contributed reagents/materials/analysis tools: PAM EEW ENO HvdP. Wrote the paper: MM VB GPB.