About the Authors

Xiaojing Yang, Chao Tang
Center for Quantitative Biology and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China

Xiaojing Yang, Kai-Yeung Lau, Volkan Sevim
Department of Bioengineering and Therapeutic Sciences, and Center for Systems and Synthetic Biology, University of California, San Francisco, California, United States of America

Corresponding Author

tangc@pku.edu.cn

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: XY KYL VS CT. Performed the experiments: XY KYL. Analyzed the data: XJ KYL. Contributed reagents/materials/analysis tools: XY KYL VS. Wrote the paper: XY KYL VS CT. Built the stochastic model: KYL. Built the in silico evolution model: VS.