About the Authors

Brian P. Anton, Alexey Fomenkov, Richard D. Morgan, Shuang-yong Xu, Dana Macelis, Richard J. Roberts
New England Biolabs, Ipswich, Massachusetts, United States of America

Yi-Chien Chang, Lina L. Faller, Zhenjun Hu, Niels Klitgord, Varun Mazumdar, Stanley Letovsky, Daniel Segrè, Charles DeLisi, Richard J. Roberts, Simon Kasif
Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

Peter Brown, Han-Pil Choi, Jyotsna Guleria, Ami Levy-Moonshine, Almaz Maksad, Lais Osmani, Revonda Pokrzywa, Rajeswari Swaminathan, Genevieve Housman, Caitlin Monahan, Krista Rochussen, Kevin Tao, Martin Steffen, Simon Kasif
Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America

Mark McGettrick, John Rachlin
Diatom Software LLC, Holliston, Massachusetts, United States of America

Benjamin Allen
Program for Evolutionary Dynamics, Harvard University, Cambridge, Massachusetts, United States of America

Benjamin Allen
Department of Mathematics, Emmanuel College, Boston, Massachusetts, United States of America

Ashok S. Bhagwat
Department of Chemistry, Wayne State University, Detroit, Michigan, United States of America

Steven E. Brenner
Department of Plant and Microbial Biology, University of California, Berkeley, California, United States of America

Linda Columbus
Department of Chemistry, University of Virginia, Charlottesville, Virginia, United States of America

Valérie de Crécy-Lagard
Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, United States of America

Donald Ferguson, Iddo Friedberg
Department of Microbiology, Miami University, Oxford, Ohio, United States of America

Giovanni Gadda
Department of Chemistry, Georgia State University, Atlanta, Georgia, United States of America

Andrei L. Osterman, Dmitry A. Rodionov, Irina A. Rodionova
Bioinformatics and Systems Biology, Sanford Burnham Medical Research Institute, La Jolla, California, United States of America

Kenneth E. Rudd
Department of Biochemistry and Molecular Biology, University of Miami, Miami, Florida, United States of America

Dieter Söll
Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

James Spain
School of Civil and Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, United States of America

Alex Bateman, Maria J. Martin, Claire O'Donovan
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom

Robert M. Blumenthal
Department of Medical Microbiology and Immunology, and Program in Bioinformatics, University of Toledo, Toledo, Ohio, United States of America

J. Martin Bollinger, Carsten Krebs
Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, United States of America

Woo-Suk Chang
Department of Biology, University of Texas-Arlington, Arlington, Texas, United States of America

Manuel Ferrer
Spanish National Research Council (CSIC), Institute of Catalysis, Madrid, Spain

Michael Y. Galperin, William Klimke
National Center for Biotechnology Information (NCBI), National Institutes of Health (NIH), Bethesda, Maryland, United States of America

Julien Gobeill, Patrick Ruch
Department of Library and Information Sciences, University of Applied Sciences Western Switzerland, Geneva, Switzerland

Julien Gobeill, Patrick Ruch
Bibliomics and Text Mining Group, Swiss Institute of Bioinformatics, Geneva, Switzerland

Daniel Haft, Ramana Madupu, Granger Sutton
J. Craig Venter Institute, Rockville, Maryland, United States of America

John Hunt
Biological Sciences, Columbia University, New York, New York, United States of America

Peter Karp
Bioinformatics Research Group, Artificial Intelligence Center, SRI International, Menlo Park, California, United States of America

Jeffrey H. Miller
Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Bernhard Palsson
Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America

Aaron Setterdahl
Department of Chemistry, Indiana University Southeast, New Albany, Indiana, United States of America

John Tate
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, United Kingdom

Alexander Yakunin, Dmitri Tchigvintsev
Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada

Germán Plata, Jie Hu, Dennis Vitkup
Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

Germán Plata
Integrated Program in Cellular, Molecular, Structural, and Genetic Studies, Columbia University, New York, New York, United States of America

Russell Greiner
Department of Computing Science, University of Alberta, Edmonton, Alberta, Canada

David Horn
School of Physics and Astronomy, Tel Aviv University, Tel Aviv, Israel

Kimmen Sjölander
Berkeley Phylogenomics Group, University of California, Berkeley, California, United States of America

Steven L. Salzberg
Departments of Medicine and Biostatistics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.