About the Authors

Karin Voordeckers

Contributed equally to this work with: Karin Voordeckers, Chris A. Brown

Affiliations VIB Laboratory for Systems Biology, Leuven, Belgium, CMPG Laboratory for Genetics and Genomics, KU Leuven, Leuven, Belgium

Chris A. Brown

Contributed equally to this work with: Karin Voordeckers, Chris A. Brown

Affiliations VIB Laboratory for Systems Biology, Leuven, Belgium, CMPG Laboratory for Genetics and Genomics, KU Leuven, Leuven, Belgium, Fathom Information Design, Boston, Massachusetts, United States of America, Faculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge, Massachusetts, United States of America, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, United States of America

Kevin Vanneste

Affiliations VIB Department of Plant Systems Biology, Gent, Belgium, Department of Plant Biotechnology and Bioinformatics, Ghent University, Gent, Belgium

Elisa van der Zande

Affiliations VIB Laboratory for Systems Biology, Leuven, Belgium, CMPG Laboratory for Genetics and Genomics, KU Leuven, Leuven, Belgium

Arnout Voet

Affiliation Laboratory for Molecular en Structural Biology, KU Leuven, Leuven, Belgium

Steven Maere

Steven.Maere@psb.vib-ugent.be (SM); Kevin.Verstrepen@biw.vib-kuleuven.be (KJV)

Affiliations VIB Department of Plant Systems Biology, Gent, Belgium, Department of Plant Biotechnology and Bioinformatics, Ghent University, Gent, Belgium

Kevin J. Verstrepen

Steven.Maere@psb.vib-ugent.be (SM); Kevin.Verstrepen@biw.vib-kuleuven.be (KJV)

Affiliations VIB Laboratory for Systems Biology, Leuven, Belgium, CMPG Laboratory for Genetics and Genomics, KU Leuven, Leuven, Belgium

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: C. Brown, S. Maere, K. Verstrepen. Performed the experiments: K. Voordeckers, C. Brown, E. van der Zande. Analyzed the data: K. Voordeckers, C. Brown, K. Vanneste, A. Voet, S. Maere, K. Verstrepen. Wrote the paper: K. Voordeckers, C. Brown, K. Vanneste, A. Voet, S. Maere, K. Verstrepen. Carried out molecular evolution analyses: C. Brown, K. Vanneste, S. Maere. Carried out structural analyses: A. Voet.