About the Authors

Sona Kang

Affiliations Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Peter Akerblad

Contributed equally to this work with: Peter Akerblad, Riku Kiviranta

Affiliations Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, AstraZeneca R&D Mölndal, Mölndal, Sweden

Riku Kiviranta

Contributed equally to this work with: Peter Akerblad, Riku Kiviranta

Address Current address: Department of Medical Biochemistry and Genetics, University of Turku, Finland

Affiliation Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, and Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Rana K. Gupta

Address Current address: Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology and Division of Metabolism and Chronic Disease, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Shingo Kajimura

Address Current address: Diabetes Center and Department of Cell and Tissue Biology, University of California at San Francisco, San Francisco, United States of America

Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Cancer Biology and Division of Metabolism and Chronic Disease, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

Michael J. Griffin

Affiliations Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Jie Min

Affiliations Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Roland Baron

Affiliation Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, and Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Evan D. Rosen

erosen@bidmc.harvard.edu

Affiliations Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

One author (PA) is employed by a commercial entity (AstraZeneca), but there are no restrictions put by this company to publish this work or make data or materials available.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: SoK EDR RB RK ShK RG MG PA. Performed the experiments: SoK RK MG JM. Analyzed the data: SoK RK EDR RB. Contributed reagents/materials/analysis tools: RK RB MG. Wrote the paper: EDR SoK.