About the Authors

Hye Ji Cha

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Michelle Byrom

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Paul E. Mead

Affiliation Department of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

Andrew D. Ellington

Affiliations Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America, Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, United States of America

John B. Wallingford

wallingford@mail.utexas.edu (JBW); marcotte@icmb.utexas.edu (EMM)

Affiliations Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America, Howard Hughes Medical Institute & Section of Molecular Cell and Developmental Biology, University of Texas at Austin, Austin, Texas, United States of America

Edward M. Marcotte

wallingford@mail.utexas.edu (JBW); marcotte@icmb.utexas.edu (EMM)

Affiliations Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America, Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas, United States of America

Competing Interests

A patent application based on this work has been filed. The authors have declared that no other competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: HJC JBW EMM. Performed the experiments: HJC MB. Analyzed the data: HJC JBW EMM. Contributed reagents/materials/analysis tools: PEM ADE. Wrote the paper: HJC ADE JBW EMM.