About the Authors

Tommy L. Lewis Jr

Affiliations Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America, Program in Molecular and Computational Biology, University of Southern California, Los Angeles, California, United States of America

Tianyi Mao

Address Current address: Vollum Institute, Oregon Health Science University, Portland, Oregon, United States of America

Affiliation Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America

Don B. Arnold

darnold@usc.edu

Affiliations Department of Biological Sciences, University of Southern California, Los Angeles, California, United States of America, Program in Molecular and Computational Biology, University of Southern California, Los Angeles, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: DBA TLL TM. Performed the experiments: TLL TM. Analyzed the data: DBA TLL TM. Wrote the paper: DBA TLL TM.