About the Authors

Merel Gijsen

Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Peter King

Affiliation Oncology Discovery Research and Early Development, Johnson & Johnson Pharmaceutical Research and Development, Janssen Pharmaceutica, Beerse, Belgium

Tim Perera

Affiliation Oncology Discovery Research and Early Development, Johnson & Johnson Pharmaceutical Research and Development, Janssen Pharmaceutica, Beerse, Belgium

Peter J. Parker

Affiliations Protein Phosphorylation Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom, Division of Cancer Studies, King's College School of Medicine, Guy's Hospital, London, United Kingdom

Adrian L. Harris

Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Banafshé Larijani

Affiliation Cell Biophysics Laboratory, London Research Institute, Cancer Research UK, London, United Kingdom

Anthony Kong

Anthony.kong@imm.ox.ac.uk

Affiliation Molecular Oncology Laboratories, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Competing Interests

Tim Perera and Peter King are employees and small share-holders of Johnson & Johnson Pharmaceutical Research & Development. This Competing Interest does not alter our adherence to all the PLoS Biology policies on sharing data and materials, or to the Creative Commons Attribution License in the event of publication.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MG PK AK. Performed the experiments: MG PK AK. Analyzed the data: MG PK TP AK. Contributed reagents/materials/analysis tools: ALH BL AK. Wrote the paper: PK AK. Helped in the interpretation of data and suggested experiments: PJP ALH BL.