About the Authors
Neurorestoration Group, Wolfson CARD, King's College London, Guy's Campus, London, United Kingdom
Henry Wellcome LINE, Dorothy Hodgkin Building, Bristol University, Bristol, United Kingdom
School of Biological Sciences, Royal Holloway-University of London, Egham, Surrey, United Kingdom
The authors Ping K. Yip, Liang-Fong Wong and Stephen McMahon would like to declare competing financial interests in relation to this work. There is a patent application submitted by King's College London and Oxford BioMedica Ltd entitled: System for delivering neuronal calcium sensor-1 (NCS-1) (International Application No.: PCT/GB2006/003367). The abstract on the application is: The present invention provides a system capable of delivering neuronal calcium sensor-1 (NCS-1), or a nucleotide sequence encoding NCS-1 to a target cell, for promoting neurite outgrowth. The system may be used in the manufacture of a pharmaceutical composition for the treatment of a condition such as spinal cord injury.
The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: PKY. Performed the experiments: PKY TAS. Analyzed the data: PKY TAS. Contributed reagents/materials/analysis tools: PKY LFW RJYM. Wrote the paper: PKY TAS SBM.