About the Authors

Robert K. Bradley

Contributed equally to this work with: Robert K. Bradley, Xiao-Yong Li

Affiliations Department of Mathematics, University of California Berkeley, Berkeley, California, United States of America, Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

Xiao-Yong Li

Contributed equally to this work with: Robert K. Bradley, Xiao-Yong Li

Affiliations Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Cole Trapnell

Affiliation Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

Stuart Davidson

Affiliation Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Lior Pachter

Affiliations Department of Mathematics, University of California Berkeley, Berkeley, California, United States of America, Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

Hou Cheng Chu

Affiliation Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Leath A. Tonkin

Affiliations California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America, Vincent J. Coates Genome Sequencing Laboratory, University of California Berkeley, Berkeley, California, United States of America

Mark D. Biggin

Affiliation Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Michael B. Eisen

mbeisen@lbl.gov

Affiliations Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, California, United States of America, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America, California Institute for Quantitative Biosciences, University of California Berkeley, Berkeley, California, United States of America

Competing Interests

MBE is a co-founder and member of the Board of Directors of PLoS.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: RKB XYL MDB MBE. Performed the experiments: XYL HCC LAT. Analyzed the data: RKB CT SD LP MBE. Contributed reagents/materials/analysis tools: RKB CT LAT. Wrote the paper: RKB MBE.