About the Authors

Jinglan Liu

Affiliation Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Zhe Zhang

Affiliation Center for Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Masashige Bando

Affiliation Laboratory of Chromosome Structure and Function, Department of Biological Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama City, Kanagawa, Japan

Takehiko Itoh

Affiliation Laboratory of Chromosome Structure and Function, Department of Biological Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama City, Kanagawa, Japan

Matthew A. Deardorff

Affiliations Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Dinah Clark

Affiliation Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Maninder Kaur

Affiliation Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Stephany Tandy

Affiliation Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Tatsuro Kondoh

Affiliation Division of Developmental Disability, Misakaenosono Mutsumi Developmental, Medical, and Welfare Center, Isahaya, Japan

Eric Rappaport

Affiliation NAPCORE, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Nancy B. Spinner

Affiliations Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Hugo Vega

Affiliation Instituto de Genética, Universidad Nacional de Colombia, Bogotá, Colombia

Laird G. Jackson

Affiliation Department of Obstetrics and Gynecology, Drexel University School of Medicine, Philadelphia, Pennsylvania, United States of America

Katsuhiko Shirahige

Affiliation Laboratory of Chromosome Structure and Function, Department of Biological Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama City, Kanagawa, Japan

Ian D. Krantz

ian2@mail.med.upenn.edu

Affiliations Division of Human Genetics, Abramson Research Institute, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: KS IDK. Performed the experiments: JL MB TI. Analyzed the data: JL ZZ MB. Contributed reagents/materials/analysis tools: MAD DC MK ST TK ER NBS HV LGJ. Wrote the paper: JL ZZ IDK. Figure preparation: ZZ JL KS IDK.