About the Authors

John G Albeck, John M Burke, Sabrina L Spencer, Peter K Sorger
Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

John M Burke, Douglas A Lauffenburger, Peter K Sorger
Biological Engineering Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Sabrina L Spencer, Douglas A Lauffenburger
Computational and Systems Biology Initiative, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

peter_sorger@hms.harvard.edu

Competing Interests

PKS is a member of the board of directors of Applied Precision Inc., manufacturer of the microscopes used in this study.

Author Contributions

JGA, JMB, SLS, DAL, and PKS worked closely together to design, perform and interpret the experiments; JGA and PKS wrote the paper.