About the Authors

Jose Silva, Ornella Barrandon, Jennifer Nichols, Jitsutaro Kawaguchi, Thorold W Theunissen, Austin Smith
Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge, United Kingdom

Jose Silva, Ornella Barrandon, Jitsutaro Kawaguchi, Thorold W Theunissen, Austin Smith
Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Jennifer Nichols
Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom

Corresponding Authors

Competing Interests

A patent application based on this work has been filed with the United Kingdom patent office by the University of Cambridge (inventors Jose Silva and Austin Smith).

Author Contributions

JS and OB contributed equally to the generation and experimental characterisation of iPS cells. JN produced chimaeras. JK performed Southern hybridisation. and TT performed real time RT-PCR measurements. AS and JS designed and supervised the study and wrote the paper.