About the Authors

Ashton W Powell

Affiliations Neuroscience Center, Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America , Curriculum in Neuroscience, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Takayuki Sassa

Affiliation Neuroscience Center, Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Yongqin Wu

Affiliation Neuroscience Center, Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Marc Tessier-Lavigne

Affiliation Genentech, South San Francisco, California, United States of America

Franck Polleux

To whom correspondence should be addressed. E-mail: polleux@med.unc.edu

Affiliation Neuroscience Center, Department of Pharmacology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AP performed the experiments, analyzed the data presented in all figures except those indicated below, and wrote the paper with FP. TS performed the experiments and analyzed the data presented in Figures 10 and S12. TS provided feedback on the manuscript. YW performed all the in situ hybridization experiments. MTL provided key reagents. FP conceived and designed the experiments, as well as performed the data analysis. FP supervised AP, TS, and YW, and wrote the manuscript with AP.