About the Authors

Rebecca Hunt-Newbury

Contributed equally to this work with: Rebecca Hunt-Newbury, Ryan Viveiros, Robert Johnsen

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Ryan Viveiros

Contributed equally to this work with: Rebecca Hunt-Newbury, Ryan Viveiros, Robert Johnsen

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Robert Johnsen

Contributed equally to this work with: Rebecca Hunt-Newbury, Ryan Viveiros, Robert Johnsen

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Allan Mah

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Dina Anastas

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Lily Fang

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Erin Halfnight

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

David Lee

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

John Lin

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Adam Lorch

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Sheldon McKay

Address ¤ Current address: Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

Affiliation Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

H. Mark Okada

Affiliation Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

Jie Pan

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Ana K Schulz

Affiliation Institut für Genetik, Technische Universität Braunschweig, Braunschweig, Germany

Domena Tu

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Kim Wong

Affiliation Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

Z Zhao

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Andrey Alexeyenko

Affiliation Center for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, Sweden

Thomas Burglin

Affiliation Department of Biosciences, Karolinska Institutet, Huddinge, Sweden

Eric Sonnhammer

Affiliation Center for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, Sweden

Ralf Schnabel

Affiliation Institut für Genetik, Technische Universität Braunschweig, Braunschweig, Germany

Steven J Jones

Affiliation Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

Marco A Marra

Affiliation Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada

David L Baillie

Affiliation Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada

Donald G Moerman

To whom correspondence should be addressed. E-mail: moerman@zoology.ubc.ca

Affiliations Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada , Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DLB and DGM conceived and designed the experiments. RHN, RV, RJ, AM, DA, LF, EH, DL, JL, JP, DT, and ZZ performed the experiments. RHN, RV, AL, JP, and DGM analyzed the data. SM, HMO, AKS, KW, AA, TB, ES, RS, SJJ, MAM, and DLB contributed reagents/materials/analysis tools. RHN, RV, and DGM wrote the paper.