About the Authors

Véronique Calleja, Damien Alcor, Banafshé Larijani
Cell Biophysics Laboratory, Lincoln's Inn Fields Laboratories, London Research Institute, Cancer Research UK, London, United Kingdom

Michel Laguerre
Institut Européen de Chimie et Biologie, Pessac Cedex, France

Jongsun Park, Brian A Hemmings
Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

Borivoj Vojnovic
Advanced Technology Development Group, Gray Cancer Institute, Mount Vernon Hospital, Northwood, United Kingdom

Julian Downward
Signal Transduction Laboratory, Lincoln's Inn Fields Laboratories, London Research Institute, Cancer Research UK, London, United Kingdom

Peter J Parker
Protein Phosphorylation Laboratory, Lincoln's Inn Fields Laboratories, London Research Institute, Cancer Research UK, London, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

VC, DA, and BL were involved in the design and performed the FRET experiments. VC was responsible for the design of the molecular biology tools and performed the biochemical experiments. ML was responsible for the molecular modeling. JP, BAH, and JD provided DNA constructs. VC, DA, BV, and BL were responsible for the set-up and optimisation of two-photon FLIM. BAH and JD were involved in scientific discussions. PJP and BL supervised the project. VC, DA, PJP, and BL were involved in writing the manuscript.