About the Authors

Natarajan Kannan

Affiliations Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America , Howard Hughes Medical Institute, University of California San Diego, La Jolla, California, United States of America

Susan S Taylor

Affiliations Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America , Howard Hughes Medical Institute, University of California San Diego, La Jolla, California, United States of America

Yufeng Zhai

Affiliation Razavi-Newman Center for Bioinformatics, Salk Institute for Biological Studies, La Jolla, California, United States of America

J. Craig Venter

Affiliation J. Craig Venter Institute, Rockville, Maryland, United States of America

Gerard Manning

To whom correspondence should be addressed. E-mail: manning@salk.edu

Affiliation Razavi-Newman Center for Bioinformatics, Salk Institute for Biological Studies, La Jolla, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JCV proposed and enabled collaboration. SST conceived of collaboration and provided structural insights and critical evaluation. NK and GM conceived and designed the experiments. NK, YZ, and GM performed the experiments. NK and GM analyzed the data. YZ and JCV contributed reagents/materials/analysis tools. NK and GM wrote the paper.