About the Authors

Hurng-Yi Wang

¤ Current address: Graduate Institute of Clinical Medicine, National Taiwan University, Taipei, Taiwan

Affiliations Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan , Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America

Huan-Chieh Chien

Affiliation Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan

Naoki Osada

Affiliation Division of Biomedical Research Resources, National Institute of Biomedical Innovation, Osaka, Japan

Katsuyuki Hashimoto

Affiliation Division of Genetic Resources, National Institute of Infectious Diseases, Tokyo, Japan

Sumio Sugano

Affiliation Laboratory of Functional Genomics, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan

Takashi Gojobori

Affiliation Center of Information Biology, National Institute of Genetics, Mishima, Japan

Chen-Kung Chou

Affiliation Department of Life Science, Chang Gung University, Tao-Yuan, Taiwan

Shih-Feng Tsai

Affiliation Division of Molecular and Genomic Medicine, National Health Research Institute, Miaoli, Taiwan

Chung-I Wu

To whom correspondence should be addressed. E-mail: ciwu@uchicago.edu (CIW); ckshen@ccvax.sinica.edu.tw (CKJS)

Affiliation Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, United States of America

C.-K. James Shen

To whom correspondence should be addressed. E-mail: ciwu@uchicago.edu (CIW); ckshen@ccvax.sinica.edu.tw (CKJS)

Affiliation Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KH, CKC, SFT,CIW, and CKJS conceived and designed the experiments. HYW, HCC, and NO performed the experiments. HYW, HCC, NO, and CKJS analyzed the data. KH, SS, TG, CKC, and SFT contributed reagents/materials/analysis tools. HYW, CIW, and CKJS wrote the paper.