About the Authors

David C Hess

To whom correspondence should be addressed. E-mail: dhess@princeton.edu

Affiliations Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America , Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

Wenyun Lu

Affiliations Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America , Department of Chemistry, Princeton University, Princeton, New Jersey, United States of America

Joshua D Rabinowitz

Affiliations Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America , Department of Chemistry, Princeton University, Princeton, New Jersey, United States of America

David Botstein

Affiliations Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America , Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DCH, JDR, and DB conceived and designed the experiments. DCH and WL performed the experiments. DCH, WL, JDR, and DB analyzed the data. DCH and WL contributed reagents/materials/analysis tools. DCH, JDR, and DB wrote the paper.