About the Authors

Nizar N Batada

To whom correspondence should be addressed. E-mail: nizar.batada@utoronto.ca (NNB); l.d.hurst@bath.ac.uk (LDH); tyers@mshri.on.ca (MT)

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada , Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

Teresa Reguly

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Ashton Breitkreutz

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Lorrie Boucher

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada , Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Canada

Bobby-Joe Breitkreutz

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

Laurence D Hurst

Contributed equally to this work with: Laurence D Hurst, Mike Tyers

To whom correspondence should be addressed. E-mail: nizar.batada@utoronto.ca (NNB); l.d.hurst@bath.ac.uk (LDH); tyers@mshri.on.ca (MT)

Affiliation Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom

Mike Tyers

Contributed equally to this work with: Laurence D Hurst, Mike Tyers

To whom correspondence should be addressed. E-mail: nizar.batada@utoronto.ca (NNB); l.d.hurst@bath.ac.uk (LDH); tyers@mshri.on.ca (MT)

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada , Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

NNB, LDH, and MT conceived and designed the experiments. NNB and LDH performed the experiments. NNB, LDH, and MT analyzed the data. NNB, TR, AB, LB, BJB, LDH, and MT contributed reagents/materials/analysis tools. NNB, LDH, and MT wrote the paper.